The aCCR(2)ual of M2 Macrophages Provides Some Breathing Room.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28686859.
- Also identified by DOI 10.1016/j.stem.2017.06.006.
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Abstract
Lung tissue can robustly regenerate functional alveolar units after injury, but the mechanisms are unknown. Lechner et al. (2017) in this issue of Cell Stem Cell demonstrate that lung regeneration is facilitated by bone-marrow-derived myeloid cells that are recruited to the lung through a CCL2-CCR2 chemokine axis and by IL-13 expressing innate lymphoid cells.
Medical subject headings
- Chemokine CCL2
- Lung
- Lung Injury
- Macrophages, Alveolar
- Receptors, CCR2
- Regeneration