Generation of Human Hair Cells In Vitro: Is It All about How the Wnt Blows?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28686861.
- Also identified by DOI 10.1016/j.stem.2017.06.007.
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Abstract
Screening for small molecules or drugs that can protect or restore mechanosensory hair cells has been hampered by limited cell numbers. In Nature Biotechnology, Koehler et al. (2017) have developed a human organoid-based approach using basic developmental principles to generate large numbers of bonafide hair cells in vitro.
Medical subject headings
- Hair Cells, Auditory
- Mechanotransduction, Cellular
- Wnt Signaling Pathway