Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28686867.
- Also identified by DOI 10.1016/j.stem.2017.06.001.
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Abstract
Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue.
Medical subject headings
- Colon
- Organoids
- Pluripotent Stem Cells