Modeling the Glomerular Filtration Barrier: Are You Kidney-ing Me?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28686869.
- Also identified by DOI 10.1016/j.stem.2017.06.008.
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Abstract
Podocyte depletion drives kidney disease and kidney failure progression, but podocyte complexity at the glomerular filtration barrier is difficult to model in vitro. In Nature Biomedical Engineering, Musah et al. (2017) developed a multifluidic device with iPS-derived podocytes mimicking a functional glomerular filtration barrier that elevates standards for modeling glomerular diseases.
Medical subject headings
- Induced Pluripotent Stem Cells
- Kidney Diseases
- Models, Biological
- Podocytes