Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28686871.
- Also identified by DOI 10.1016/j.stem.2017.06.002.
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Abstract
Dormant hematopoietic stem cells (dHSCs) display superior serial reconstitution capacity compared to active HSCs, although their role in normal hematopoiesis has not been thoroughly investigated. Recently in Cell, Cabezas-Wallscheid et al. (2017) demonstrate involvement of retinoic acid signaling in murine dHSCs for preservation of the HSC pool.
Medical subject headings
- Hematopoiesis
- Hematopoietic Stem Cells
- Tretinoin