Rhabdomyolysis and AKI with Atorvastatin and Sitagliptin Use in the Setting of Low 25-Hydroxyvitamin D Levels.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28707259.
- Also identified by DOI 10.1007/s11606-017-4115-x and PMC identifier 5602766.
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Abstract
We report a case of an 86-year-old woman admitted to the hospital with rhabdomyolysis and acute kidney injury 3 weeks after starting sitagliptin while on long-term atorvastatin therapy. She also had low levels of 25-hydroxyvitamin D and mild chronic kidney disease, which may have contributed to the development of rhabdomyolysis. A review of the literature reveals four previous reports of this drug interaction in elderly patients, some with underlying kidney disease.
Medical subject headings
- Acute Kidney Injury
- Atorvastatin
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Rhabdomyolysis
- Sitagliptin Phosphate
- Vitamin D