Processing-structure relationships of poly(ethylene glycol)-modified liposomes.
basic_science · Level V
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- Record sourced from PubMed, PMID 28730191.
- Also identified by DOI 10.1039/c7sm00960g and PMC identifier 11112619.
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Abstract
Liposomes with PEG-modified surfaces are amenable to nanocarrier applications and can be prepared via two PEGylated lipid incorporation routes: before and after extrusion (i.e., co-extrusion and post-insertion, respectively). The current study quantifies the processing influence on PEG chain partitioning between the interior and exterior liposome surfaces for the first time using small angle neutron scattering.