Multicellular Vascularized Engineered Tissues through User-Programmable Biomaterial Photodegradation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28737278.
- Also identified by DOI 10.1002/adma.201703156 and PMC identifier 5628157.
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Abstract
A photodegradable material-based approach to generate endothelialized 3D vascular networks within cell-laden hydrogel biomaterials is introduced. Exploiting multiphoton lithography, microchannel networks spanning nearly all size scales of native human vasculature are readily generated with unprecedented user-defined 4D control. Intraluminal channel architectures of synthetic vessels are fully customizable, providing new opportunities for next-generation microfluidics and directed cell function.
Medical subject headings
- Tissue Engineering