Getting Drugs Across Biological Barriers.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28752600.
- Also identified by DOI 10.1002/adma.201606596 and PMC identifier 5683089.
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Abstract
The delivery of drugs to a target site frequently involves crossing biological barriers. The degree and nature of the impediment to flux, as well as the potential approaches to overcoming it, depend on the tissue, the drug, and numerous other factors. Here an overview of approaches that have been taken to crossing biological barriers is presented, with special attention to transdermal drug delivery. Technology and knowledge pertaining to addressing these issues in a variety of organs could have a significant clinical impact.
Medical subject headings
- Pharmaceutical Preparations