Drugs, Bugs, and Cancer: Fusobacterium nucleatum Promotes Chemoresistance in Colorectal Cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28753421.
- Also identified by DOI 10.1016/j.cell.2017.07.018.
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Abstract
The tumor microenvironment has recently been shown to play decisive roles in chemotherapeutic response. In this issue of Cell, Yu et al. add to these findings by identifying the bacterium Fusobacterium nucleatum as a previously unrecognized chemoresistance mediator in colorectal cancer, thereby establishing the microbiota as a potential therapeutic target.
Medical subject headings
- Colorectal Neoplasms
- Fusobacterium nucleatum