Radiation-induced focal cortical necrosis of the femur presenting as a lytic lesion.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28755281.
- Also identified by DOI 10.1007/s00256-017-2715-5.
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Abstract
Management of soft tissue sarcomas is often complicated, requiring radiation before and in some cases after limb-sparing surgery. Radiation necrosis is a severe complication after radiation treatment and is typically dose related and involves medullary bone. We report on two cases of hitherto unreported focal circumscribed intra-cortical lytic lesions within the radiation portal, which appeared 19 months and 31 months, respectively, after the conclusion of radiation treatment. Both patients had a history of soft tissue sarcoma treated with radiation (66 Gy) and surgical resection. Biopsy of these lesions showed necrotic bone attributed to radiation.
Medical subject headings
- Femur
- Liposarcoma
- Radiation Injuries
- Sarcoma
Anatomy
- femur