Once Blind, Now We See GLP-1 Molecular Action.

Mayer, John P; Tschöp, Matthias H; DiMarchi, Richard D · Cell Metab · 2017

editorial · Level V

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Abstract

The macromolecular mechanics of GLP-1 with its cell surface receptor came into focus as two landmark publications recently published in Nature collectively herald advancement in structure-based design for a receptor class of great therapeutic importance (Jazayeri et al., 2017; Zhang et al., 2017).

Medical subject headings