Cholangiocytes: No Longer Cinderellas to the Hepatic Regenerative Response.

Alison, Malcolm R · Cell Stem Cell · 2017

editorial · Level V

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Abstract

Biliary ductal cells proliferate from the portal areas of chronically damaged livers, but their significance to regeneration has been controversial. A recent article in Nature by Raven et al. (2017) now shows that blocking hepatocyte replication is essential for the hepatic differentiation of ductular cells after liver damage.

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