Association between hepatitis C virus and chronic kidney disease: heterogeneity begets heterogeneity.
Level V
Where this comes from
- Record sourced from PubMed, PMID 28807261.
- Also identified by DOI 10.1016/j.kint.2017.04.023 and PMC identifier 5895479.
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Abstract
Epidemiologic studies examining the association between hepatitis C virus and chronic kidney disease have yielded conflicting findings. Analyzing data from a Taiwanese cohort, Lai and colleagues report a novel finding that the odds of chronic kidney disease were nearly 3-fold higher in hepatitis C virus-infected persons with genotype 2 compared with genotype 1. Hepatitis C virus genotype distributions differ in regions around the world. Can genotypic differences in chronic kidney disease risk explain some of the heterogeneity in prior studies?
Medical subject headings
- Hepacivirus
- Renal Insufficiency, Chronic