Deconstructing interstitial fibrosis and tubular atrophy: a step toward precision medicine in renal transplantation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28807264.
- Also identified by DOI 10.1016/j.kint.2017.04.041.
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Abstract
The prerequisite for successful treatment is an accurate diagnosis, a concept coined precision medicine. Progression of interstitial fibrosis and tubular atrophy is widely considered the natural course for all transplanted kidneys. In this issue, Gosset et al. describe discrete disease entities in individual patients and their contribution to interstitial fibrosis and tubular atrophy and its progression. This represents a major step forward in stratifying patients for targeted treatment trials (i.e., a step toward precision medicine in renal transplantation).
Medical subject headings
- Kidney Transplantation
- Precision Medicine