Prothrombin fragment F1+2 in plasma and urine during total hip arthroplasty.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 28831236.
- Also identified by DOI 10.1016/j.jor.2017.08.001 and PMC identifier 5555093.
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Abstract
To study the time course and correlation of prothrombin fragment (F1 + 2) in plasma and urine during THA. F1 + 2 concentrations were recorded at four time-points during THA. F1 + 2 increased during surgery. In contrast to urine, plasma F1 + 2 was temporarily reduced the first postoperative day. At day six, plasma F1 + 2 was significantly elevated indicating on-going thrombin activation, while urine F1 + 2 was normalized. The response in coagulation to operative trauma can be recorded with F1 + 2 both in plasma and urine. We were not able to demonstrate any correlation of F1 + 2 in plasma and urine later in the postoperative period.
Anatomy
- hip