Considerations for the Full Global Withdrawal of Oral Polio Vaccine After Eradication of Polio.
Where this comes from
- Record sourced from PubMed, PMID 28838193.
- Also identified by DOI 10.1093/infdis/jix105 and PMC identifier 5853572.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Eliminating the risk of polio from vaccine-derived polioviruses is essential for creating a polio-free world, and eliminating that risk will require stopping use of all oral polio vaccines (OPVs) once all types of wild polioviruses have been eradicated. In many ways, the experience with the global switch from trivalent OPV (tOPV) to bivalent OPV (bOPV) can inform the eventual full global withdrawal of OPV. Significant preparation will be needed for a thorough, synchronized, and full withdrawal of OPV, and such preparation would be aided by setting a reasonably firm date for OPV withdrawal as far in advance as possible, ideally at least 24 months. A shorter lead time would provide valuable flexibility for decisions about when to stop use of OPV in the context of uncertainty about whether or not all types of wild polioviruses had been eradicated, but it might increase the cost of OPV withdrawal.
Medical subject headings
- Disease Eradication
- Disease Outbreaks
- Global Health
- Poliomyelitis
- Poliovirus Vaccine, Oral