Cancer Evolution Constrained by the Immune Microenvironment.

McGranahan, Nicholas; Swanton, Charles · Cell · 2017

editorial · Level V

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Abstract

Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.

Medical subject headings