Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28842288.
- Also identified by DOI 10.1016/j.injury.2017.08.004.
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Abstract
Malignant neoplasms infiltrating the chest wall often requires resection of the thoracic wall. To replace the defect, Gore-Tex<sup>®</sup> is usually employed as the gold standard material, however, Gore-Tex<sup>®</sup> is inert and not degradable. Novel materials are nowadays available which allow a full bio-integration due to their non-toxic degradability. Additionally, stem cell seeding has the capacity to reduce inflammatory response towards such grafts, thus integrating it better into the host organism.
Medical subject headings
- Stem Cells
- Thoracic Wall
- Tissue Scaffolds