Creatine Fuels the Thermic Effect of Feeding.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28844879.
- Also identified by DOI 10.1016/j.cmet.2017.08.010.
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Abstract
The current obesity epidemic has focused a great deal of attention on cellular pathways of energy expenditure. While a crucial part of this process is diet-induced thermogenesis, the underlying mechanisms have remained unexplained. In this issue of Cell Metabolism, Kazak et al. (2017) describe a new thermogenic pathway in adipocytes that responds to diet overload, involving creatine cycling. These data suggest that this pathway might limit weight gain during overnutrition.
Medical subject headings
- Creatine
- Diet
- Obesity
- Thermogenesis