Can FSH influence longevity?
Level V
Where this comes from
- Record sourced from PubMed, PMID 28856803.
- Also identified by DOI 10.1111/acel.12663 and PMC identifier 5595675.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
It was recently reported that the extragonadal actions of follicle-stimulating hormone (FSH) include regulation of brown and white adipose tissue function and thermogenesis. Based on these findings and on our evidence for reduced FSH levels and enhanced thermogenesis in long-lived growth hormone (GH)-deficient mice and GH-resistant mice, we suggest that FSH may have a role in the control of aging and longevity. We speculate that alterations in FSH secretion may represent one of the mechanisms of trade-offs between reproduction and aging.
Medical subject headings
- Fertility
- Follicle Stimulating Hormone
- Growth Hormone
- Longevity
- Reproduction
- Sexual Maturation