Spinal Cord Astrocytoma with Isocitrate Dehydrogenase 1 Gene Mutation.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 28866063.
- Also identified by DOI 10.1016/j.wneu.2017.08.142.
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Abstract
In 2016, the World Health Organization updated its classification of tumors, adding genetic profiles to the conventional histopathologic typing. The authors present herein the first case of a 44-year-old female with isocitrate dehydrogenase-mutant World Health Organization grade II diffuse spinal astrocytoma diagnosed on the basis of both histopathologic and genetic findings. The present case underscores the significant role of a molecular genetic analysis in the differential diagnosis of intramedullary spinal gliomas.
Medical subject headings
- Astrocytoma
- Isocitrate Dehydrogenase
- Spinal Cord Neoplasms