Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository.

Wan, Joy; Steiner, Jack; Baselga, Eulalia; Blei, Francine; Cordisco, Maria; Garzon, Maria C; Goddard, Deborah S; Haggstrom, Anita et al. · J Pediatr · 2017

retrospective_cohort · Level III

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Abstract

The cause of PHACE syndrome is unknown. In a study of 218 patients, we examined potential prenatal risk factors for PHACE syndrome. Rates of pre-eclampsia and placenta previa in affected individuals were significantly greater than in the general population. No significant risk factor differences were detected between male and female subjects.

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