The Liver as a Hub in Thermogenesis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28877451.
- Also identified by DOI 10.1016/j.cmet.2017.08.018.
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Abstract
Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al. (2017) demonstrate in cold-exposed mice that liver-generated acylcarnitines are required to fuel thermogenesis.
Medical subject headings
- Adipose Tissue, Brown
- Thermogenesis