Renal denervation: What happened, and why?

Shishehbor, Mehdi H; Hammad, Tarek A; Thomas, George · Cleve Clin J Med · 2017

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Abstract

Despite promising results in initial trials, renal denervation failed to achieve its efficacy end points as a treatment for resistant hypertension in the SYMPLICITY HTN-3 trial, the largest trial of this treatment to date (N Engl J Med 2014; 370:1393-1401). Is renal denervation dead, or will future trials and newer technology revive it?

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