Open Sesame: Open Chromatin Regions Shed Light onto Non-coding Risk Variants.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28886358.
- Also identified by DOI 10.1016/j.stem.2017.08.006.
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Abstract
Human genetics and stem cell biology have advanced neurobiology for neurodevelopmental psychiatric disorders. In this issue of Cell Stem Cell, Forrest et al. (2017) demonstrate that studying the landscape of open chromatin regions in stem cell-derived neurons helps functional interpretation of non-coding genetic variants associated with these diseases.
Medical subject headings
- Induced Pluripotent Stem Cells
- Sesamum