Crowd Control: E7 Conservation Is the Key to Cancer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 28886377.
- Also identified by DOI 10.1016/j.cell.2017.08.033.
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Abstract
Several human papillomavirus type 16 (HPV16) oncoproteins contribute to cellular transformation in vitro. In this issue of Cell, Mirabello and colleagues use high-throughput sequencing data to assess the diversity of HPV16 isolates from human patients. These data suggest that the E7 oncoprotein is the fundamental contributor to in vivo carcinogenesis.
Medical subject headings
- Human papillomavirus 16
- Oncogene Proteins, Viral