TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28888322.
- Also identified by DOI 10.1016/j.cell.2017.08.019.
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Abstract
Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.
Medical subject headings
- Awards and Prizes
- Cells
- Physiology
- Signal Transduction
- TOR Serine-Threonine Kinases