Changes in dynamic lung mechanics after lung volume reduction coil treatment of severe emphysema.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 28893857.
- Also identified by DOI 10.1136/thoraxjnl-2017-210118.
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Abstract
We assessed the relationships between changes in lung compliance, lung volumes and dynamic hyperinflation in patients with emphysema who underwent bronchoscopic treatment with nitinol coils (coil treatment) (n=11) or received usual care (UC) (n=11). Compared with UC, coil treatment resulted in decreased dynamic lung compliance (C<sub>Ldyn</sub>) (p=0.03) and increased endurance time (p=0.010). The change in C<sub>Ldyn</sub> was associated with significant improvement in FEV<sub>1</sub> and FVC, with reduction in residual volume and intrinsic positive end-expiratory pressure, and with increased inspiratory capacity at rest/and at exercise. The increase in end-expiratory lung volume (EELV) during exercise (EELV<sub>dyn-ch</sub>=EELV<sub>isotime</sub> EELV<sub>rest</sub>) demonstrated significant attenuation after coil treatment (p=0.02).
Medical subject headings
- Physical Endurance
- Pneumonectomy
- Pulmonary Emphysema
- Respiratory Mechanics