Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (<i>Danio rerio</i>).

Cong, Lin; Wang, Zeguan; Chai, Yuming; Hang, Wei; Shang, Chunfeng; Yang, Wenbin; Bai, Lu; Du, Jiulin et al. · Elife · 2017

basic_science · Level V

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Abstract

The internal brain dynamics that link sensation and action are arguably better studied during natural animal behaviors. Here, we report on a novel volume imaging and 3D tracking technique that monitors whole brain neural activity in freely swimming larval zebrafish (<i>Danio rerio</i>). We demonstrated the capability of our system through functional imaging of neural activity during visually evoked and prey capture behaviors in larval zebrafish.

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