WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs.
basic_science · Level V
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- Record sourced from PubMed, PMID 28957499.
- Also identified by DOI 10.1093/bioinformatics/btx383 and PMC identifier 5870724.
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Abstract
WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of times faster, making it suited for metagenomics studies. OpenMP-parallelized GPL-licensed C ++ code available at https://github.com/soedinglab/wish. clovis.galiez@mpibpc.mpg.de or soeding@mpibpc.mpg.de. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Bacteriophages
- Metagenomics
- Software