MWASTools: an R/bioconductor package for metabolome-wide association studies.
other · Level V
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- Record sourced from PubMed, PMID 28961702.
- Also identified by DOI 10.1093/bioinformatics/btx477 and PMC identifier 6049002.
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Abstract
MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide association studies results. The MWASTools R package is implemented in R (version > =3.4) and is available from Bioconductor: https://bioconductor.org/packages/MWASTools/. m.dumas@imperial.ac.uk. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Metabolome
- Metabolomics
- Software