PyLasso: a PyMOL plugin to identify lassos.

Gierut, Aleksandra M; Niemyska, Wanda; Dabrowski-Tumanski, Pawel; Sulkowski, Piotr; Sulkowska, Joanna I · Bioinformatics · 2017

basic_science · Level V

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Abstract

Entanglement in macromolecules is an important phenomenon and a subject of multidisciplinary research. As recently discovered, around 4% of proteins form new entangled motifs, called lassos. Here we present the PyLasso-a PyMOL plugin to identify and analyse properties of lassos in proteins and other (bio)polymers, as well as in other biological, physical and mathematical systems. The PyLasso is a useful tool for all researchers working on modeling of macromolecules, structure prediction, properties of polymers, entanglement in fluids and fields, etc. The PyLasso and tutorial videos are available at http://pylasso.cent.uw.edu.pl. jsulkowska@cent.uw.edu.pl.

Medical subject headings