E Pluribus Unum ("Out of Many, One"): CRISPR Modeling of Myeloid Expansion.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28985519.
- Also identified by DOI 10.1016/j.stem.2017.09.013.
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Abstract
In this issue of Cell Stem Cell, Tothova et al. (2017) demonstrate a promising way to model the complex genetics of clonal hematopoiesis and myeloid disorders using CRISPR-Cas9 genome editing in human hematopoietic stem and progenitor cells. Their approach opens the door to genotype-specific pharmacologic testing.
Medical subject headings
- Gene Editing
- Neoplasms