Gut with the Program: Direct Reprogramming toward Intestinal Epithelium Realized.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28985520.
- Also identified by DOI 10.1016/j.stem.2017.09.011.
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Abstract
Intestinal organoids offer great promise for modeling intestinal diseases; however, harvesting intestinal tissue is invasive and directed hPSC differentiation protocols are laborious and costly. In this issue of Cell Stem Cell, Miura and Suzuki (2017) describe the direct conversion of somatic cells from both mice and humans into robust intestinal epithelial tissue.
Medical subject headings
- Intestinal Mucosa
- Organoids