Mononuclear Diploidy at the Heart of Cardiomyocyte Proliferation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 28985522.
- Also identified by DOI 10.1016/j.stem.2017.09.012.
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Abstract
Reporting in Nature Genetics, Patterson et al. (2017) show that adult mammalian hearts possess an innate capacity to regenerate, which depends on a small population of mononuclear diploid cardiomyocytes. These cells undergo karyokinesis and cytokinesis, raising the possibility that endogenous cardiac muscle cells can be stimulated to proliferate for myocardial repair.
Medical subject headings
- Diploidy
- Myocytes, Cardiac