SnapShot: Tissue Clearing.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 28985569.
- Also identified by DOI 10.1016/j.cell.2017.09.025.
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Abstract
Tissue clearing has become an important tool for the investigation of biological systems in three dimensions. However, many pioneering techniques were based on serendipitous discoveries. Next-generation clearing methods have been (re)designed with a better understanding of the chemistry and physics required to equalize the refractive index throughout a sample which prevents the random bending of light that clouds biological tissues.
Medical subject headings
- Histological Techniques
- Microscopy