Effects of biodegradable hydrogel spacer injection on contralateral submandibular gland sparing in radiotherapy for head and neck cancers.
biomechanical · Level V
Where this comes from
- Record sourced from PubMed, PMID 28985953.
- Also identified by DOI 10.1016/j.radonc.2017.09.017.
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Abstract
Xerostomia is the most common late toxicity after head and neck radiation. We demonstrate injection of a hydrogel spacer anteriorly displacing the submandibular gland. This procedure enables reduced dose to the displaced submandibular gland in cadaveric models of oropharynx cancer treated with IMRT, with potential implications in reducing xerostomia risk.
Medical subject headings
- Hydrogels
- Oropharyngeal Neoplasms
- Radiation Injuries
- Radiation-Protective Agents
- Radiotherapy Planning, Computer-Assisted
- Submandibular Gland
- Xerostomia