Influenza A(H5N1) Virus Infection in a Child With Encephalitis Complicated by Obstructive Hydrocephalus.

Mak, Gannon Chun Kit; Kwan, Mike Yat-Wah; Mok, Chris Ka Pun; Lo, Janice Yee Chi; Peiris, Malik; Leung, Chi Wai · Clin Infect Dis · 2018

case_report · Level V

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Abstract

A 2-year-old boy with highly pathogenic avian influenza A(H5N1) virus infection with minimal respiratory symptoms developed encephalitis complicated by obstructive hydrocephalus. Viral RNA was detectable in cerebrospinal fluid. The virus belonged to H5N1 clade 2.3.2.1b and had acquired the mammalian adaptation mutation PB2 Q591K.

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