Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 29020222.
- Also identified by DOI 10.1093/cid/cix821 and PMC identifier 5850035.
- Licence recorded as CC BY-NC-ND.
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Abstract
Fecal microbiota transplantation (FMT) may be a novel approach to eliminate multidrug-resistant bacteria from the gut and to prevent future infections. Using whole metagenome sequencing data from 8 FMT donor-recipient pairs, we identified 37 and 95 antimicrobial resistance genes that were acquired by or removed from FMT recipients, respectively.
Medical subject headings
- Clostridium Infections
- Drug Resistance, Multiple, Bacterial
- Fecal Microbiota Transplantation
- Gastrointestinal Microbiome
- Genes, MDR