High volatile anaesthetic conservation with a digital in-line vaporizer and a reflector.

Mashari, A; Fedorko, L; Fisher, J A; Klein, M; Wąsowicz, M; Meineri, M · Acta Anaesthesiol Scand · 2018

basic_science · Level V

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Abstract

A volatile anaesthetic (VA) reflector can reduce VA consumption (VAC) at the cost of fine control of its delivery and CO<sub>2</sub> accumulation. A digital in-line vaporizer and a second CO<sub>2</sub> absorber circumvent both of these limitations. We hypothesized that the combination of a VA reflector with an in-line vaporizer would yield substantial VA conservation, independent of fresh gas flow (FGF) in a circle circuit, and provide fine control of inspired VA concentrations. Prospective observational study on six Yorkshire pigs. A secondary anaesthetic circuit consisting of a Y-piece with 2 one-way valves, an in-line vaporizer and a CO<sub>2</sub> absorber in the inspiratory limb was connected to the patient's side of the VA reflector. The other side was connected to the Y-piece of a circle anaesthetic circuit. In six pigs, an inspired concentration of sevoflurane of 2.5% was maintained by the in-line vaporizer. We measured VAC at FGF of 1, 4 and 10 l/min. With the secondary circuit, VAC was 55% less than with the circle system alone at FGF 1 l/min, and independent of FGF over the range of 1-10 l/min. Insertion of a CO<sub>2</sub> absorber in the secondary circuit reduced P<sub>et</sub> CO<sub>2</sub> by 1.3-2.0 kpa (10-15 mmHg). A secondary circuit with reflector and in-line vaporizer provides highly efficient anaesthetic delivery, independent of FGF. A second CO<sub>2</sub> absorber was necessary to scavenge the CO<sub>2</sub> reflected by the anaesthetic reflector. This secondary circuit may turn any open circuit ventilator into an anaesthetic delivery unit.

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