NDEx 2.0: A Clearinghouse for Research on Cancer Pathways.
other · Level V
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- Record sourced from PubMed, PMID 29092941.
- Also identified by DOI 10.1158/0008-5472.CAN-17-0606 and PMC identifier 5679399.
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Abstract
We present NDEx 2.0, the latest release of the Network Data Exchange (NDEx) online data commons (www.ndexbio.org) and the ways in which it can be used to (i) improve the quality and abundance of biological networks relevant to the cancer research community; (ii) provide a medium for collaboration involving networks; and (iii) facilitate the review and dissemination of networks. We describe innovations addressing the challenges of an online data commons: scalability, data integration, data standardization, control of content and format by authors, and decentralized mechanisms for review. The practical use of NDEx is presented in the context of a novel strategy to foster network-oriented communities of interest in cancer research by adapting methods from academic publishing and social media. <i>Cancer Res; 77(21); e58-61. ©2017 AACR</i>.
Medical subject headings
- Computational Biology
- Internet
- Neoplasms