Vitamin C: C-ing a New Way to Fight Leukemia.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29100007.
- Also identified by DOI 10.1016/j.stem.2017.09.015.
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Abstract
Metabolic cues and (epi-)genetic factors are emerging regulators of hematopoietic stem cell (HSC) potency. Two new studies in Nature and Cell, from Agathocleous et al. (2017) and Cimmino et al. (2017), respectively, show that vitamin C regulates HSC function and suppresses leukemogenesis by modulating Tet2 activity.
Medical subject headings
- Ascorbic Acid
- Leukemia