Updated Guidelines for Metastatic Hormone-sensitive Prostate Cancer: Abiraterone Acetate Combined with Castration Is Another Standard.

Mottet, Nicolas; De Santis, Maria; Briers, Erik; Bourke, Liam; Gillessen, Silke; Grummet, Jeremy P; Lam, Thomas B; van der Poel, Henk G et al. · Eur Urol · 2018

Where this comes from

Abstract

Addition of docetaxel to androgen deprivation therapy (ADT) was recommended for patients with newly diagnosed metastatic hormone-sensitive prostate cancer (mHSPC), who are fit enough to receive docetaxel. Two recently published trials showed that the addition of abiraterone acetate plus prednisone to ADT has a clear survival benefit and acceptable overall tolerance, and should be considered as another standard of care for newly diagnosed mHSPC.