Determination of knee cartilage volume and surface area in beagle dogs: a pilot study.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 29105014.
- Also identified by DOI 10.1186/s40634-017-0109-1 and PMC identifier 5673056.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The objective of this study was to determine the cartilage volume and surface area of male and female Beagle dog knees using 3D (3 dimensional) reconstructed MRI images. Six Beagle Dogs (Canis familiaris) (3 males and 3 females) of 10-18 months old and weighing between 7.2 and 17.1 kg underwent a MRI evaluation of both knees. The data acquired allowed a 3D reconstruction of the knee and measurement of the cartilage volume and surface area. Mean knee cartilage volume (averaged over the right and left knees) of animals between 7.2 and 17.1 kg ranged from 319.7 to 647.3 mm<sup>3</sup>; while the mean knee cartilage surface area ranged from 427.14 to 757.2 mm<sup>2</sup>. There was evidence of both knee volume and surface area increasing linearly with animal bodyweight. The cartilage volume and surface area of the Beagle dog appears to correlate significantly with body weight. This study provides a reference base for future studies investigating cartilage related pathology such as osteoarthritis.