What Ignites UCP1?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 29117542.
- Also identified by DOI 10.1016/j.cmet.2017.10.012.
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Abstract
We thought we knew how the heat-producing uncoupling protein 1 in brown adipose tissue was activated: by fatty acids released upon lipid droplet breakdown in the brown adipocytes. However, two studies in this issue (Schreiber et al., 2017; Shin et al., 2017) imply that this classical model may not be valid: heat can be produced in brown fat without intracellular lipolysis.
Medical subject headings
- Adipose Tissue, Brown
- Lipolysis