Variability in Intrahousehold Transmission of Ebola Virus, and Estimation of the Household Secondary Attack Rate.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 29140442.
- Also identified by DOI 10.1093/infdis/jix579 and PMC identifier 5853870.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Transmission between family members accounts for most Ebola virus transmission, but little is known about determinants of intrahousehold spread. From detailed exposure histories, intrahousehold transmission chains were created for 94 households of Ebola survivors in Sierra Leone: 109 (co-)primary cases gave rise to 317 subsequent cases (0-100% of those exposed). Larger households were more likely to have subsequent cases, and the proportion of household members affected depended on individual and household-level factors. More transmissions occurred from older than from younger cases, and from those with more severe disease. The estimated household secondary attack rate was 18%.
Medical subject headings
- Disease Transmission, Infectious
- Family Health
- Hemorrhagic Fever, Ebola