CKD stage V in AL amyloidosis: is it too late to treat? Maybe not.
Level V
Where this comes from
- Record sourced from PubMed, PMID 29153137.
- Also identified by DOI 10.1016/j.kint.2017.07.012.
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Abstract
Ig light chain amyloidosis is a protein misfolding disease capable of causing multiorgan failure. Organ failure can be stopped by reducing the production of Ig light chain. The current study by Rezk et al. found that even patients with advanced chronic kidney disease can benefit if the serum free light chain can be substantially reduced within the first 3 months. This, if confirmed, can have a huge impact in the management of these patients.
Medical subject headings
- Immunoglobulin Light Chains
- Immunoglobulin Light-chain Amyloidosis