p-cresol sulfate and indoxyl sulfate: some clouds are gathering in the uremic toxin sky.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 29153138.
- Also identified by DOI 10.1016/j.kint.2017.06.029.
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Abstract
An increasing body of experimental and clinical evidence suggests that p-cresol sulfate and indoxyl sulfate contribute to the high cardiovascular burden in patients with chronic kidney disease. In a post hoc analysis on the HEMO trial, Shafi et al. failed to confirm an association between total p-cresol sulfate and indoxyl sulfate and cardiovascular outcomes in dialysis patients. Analytical issues and case-mix may explain the discrepant findings.
Medical subject headings
- Indican
- Sulfuric Acid Esters