Breath Volatile Organic Compound Profiling of Colorectal Cancer Using Selected Ion Flow-tube Mass Spectrometry.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 29194085.
- Also identified by DOI 10.1097/SLA.0000000000002539.
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Abstract
BACKGROUND:: Breath VOCs have the potential to noninvasively diagnose cancer. Exhaled breath samples were collected using 2-L double-layered Nalophan bags, and were analyzed using selected-ion-flow-tube mass-spectrometry. Gold-standard test for comparison was endoscopy for luminal inspection and computed tomography (CT) to confirm cancer recurrence. Three studies were conducted: RESULTS:: CONCLUSION:: This study suggests the association of a single breath biomarker with the primary presence and recurrence of CRCa. Further multicenter validation studies are required to validate these findings.
Medical subject headings
- Colorectal Neoplasms
- Mass Spectrometry
- Neoplasm Recurrence, Local
- Volatile Organic Compounds